Publications
SARS-CoV-2 Infection Activates Inflammatory Macrophages in Vascular Immune Organoids
Wang Chau, C., To, A., Au-Yeung, R.K.H., Tang, K., Xiang, Y., Ruan, D., Zhang, L., Wong, H., Zhang, S., Au, M.T., Chung, S., Song, E., Choi, D.-H., Liu, P., Yuan, S., Wen, C., and Sugimura, R. (2024). bioRxiv. doi: 10.1101/2024.03.20.585837
Taming Microglia: The Promise of Engineered Microglia in Treating Neurological Diseases
Luo, E.Y. and Sugimura, R. (2024). Journal of Neuroinflammation, 21, 19. doi: 10.1186/s12974-024-03015-9
Organoids in Concert: Engineering in Vitro Models Toward Enhanced Fidelity
Chen, Z., Sugimura, R., Zhang, Y.S., Ruan, C., and Wen, C. (2024) Aggregate, 00, e478. doi: 10.1002/agt2.478
Single-Cell Mitochondrial Variant Enrichment Resolved Clonal Tracking and Spatial Architecture in Human Embryonic Hematopoiesis
Xue, Y., Chao, Y., Lin, X., Huang, Y., Ho, J.W.K., and Sugimura, R. (2023). bioRxiv. doi: 10.1101/2023.09.18.558215
Organoid-Based Single-Cell Spatiotemporal Gene Expression Landscape of Human Embryonic Development and Hematopoiesis
Chao, Y., Xiang, Y., Xiao, J., Zheng, W., Ebrahimkhani, M.R., Yang, C., Wu, A.R., Liu, P., Huang, Y., and Sugimura, R. (2023). Signal Transduction and Targeted Therapy, 8, 230. doi: 10.1038/s41392-023-01455-y
Integrating Spatial and Single-Cell Transcriptomics Data Using Deep Generative Models With SpatialScope
Wan, X., Xiao, J., Tam, S.S.T., Cai, M., Sugimura, R., Wang, Y., Wan, X., Lin, Z., Wu, A.R., and Yang, C. (2023). Nature Communications, 14, 7848. doi: 10.1038/s41467-023-43629-w
Ex Vivo Expansion of Hematopoietic Stem Cells
Wang, Y. and Sugimura, R. (2023). Experimental Cell Research, 427(1), 113599. doi: 10.1016/j.yexcr.2023.113599.
IPSC-Derived CAR-NK Cells for Cancer Immunotherapy
Lin, X., Sun, Y., Dong, X., Liu, Z., Sugimura, R., and Xie, G. (2023). Biomedicine & Pharmacotherapy, 165, 115123. doi: 10.1016/j.biopha.2023.115123
The Role of m6A mRNA Modification in Normal and Malignant Hematopoiesis
Ma, Z., Sugimura, R., and Lui, K.O. (2023). Journal of Leukocyte Biology, qiad061. doi: 10.1093/jleuko/qiad061
Give Them Vasculature and Immune Cells – How to Fill the Gap of Organoids
Yip, S., Wang, N., and Sugimura, R. (2023). Cells Tissues Organs. doi: 10.1159/000529431
Generation of Natural Killer Cells from Human Expanded Potential Stem Cells
Ching, P. Y., Wang, C., Hang, S., Liu, P., and Sugimura, R. (2023). Journal of Visualized Experiments, 191, e64608. doi:10.3791/64608
T, NK, Then Macrophages: Recent Advances and Challenges in Adaptive Immunotherapy From Human Pluripotent Stem Cells
Hang, S., Wang, N., and Sugimura, R. (2023). Differentiation. doi: 10.1016/j.diff.2023.01.001
PD-L1 Regulates Inflammatory Programs of Macrophages From Human Pluripotent Stem Cells
Cao, H., Xiang, Y., Zhang, S., Chao, Y., Guo, J., Aurich, T., Ho, J.W.K., Huang, Y., Liu, P., and Sugimura, R. (2023). Life Science Alliance, 7 (2) e202302461. doi: 10.26508/lsa.202302461
The Prospect of Genetically Engineering Natural Killer Cells for Cancer Immunotherapy (PDF)
Poon, A.Y.C. and Sugimura, R. (2022). Biology Open, 11(12): bio059396. doi:10.1242/bio.059396
The Tumor Microenvironment Reprograms Immune Cells (PDF)
Cao, H., Gao, S., Jogani, R., and Sugimura, R. (2022). Cellular Reprogramming, 24(6), 343-352. doi: 10.1089/cell.2022.0047
Combating Challenges in CAR-T Cells With Engineering Immunology (PDF)
Wang, C.Y., Ting Cheung, S.P., and Sugimura, R. (2022), Frontiers in Cell and Developmental Biology, 10:969020. doi: 10.3389/fcell.2022.969020
COVID-19: Locked in a Pro-Inflammatory State (PDF)
Wang Chau, C. and Sugimura, R. (2022) eLife, 11:e80699. doi: 10.7554/eLife.80699
ZFP281-BRCA2 Prevents R-loop Accumulation During DNA Replication (PDF)
Wang, Y., Ma, B., Liu, X., Gao, G., Che, Z., Fan, M., Meng, S., Zhao, X., Sugimura, R., Cao, H., Zhou, Z., Xie, J., Lin, C., and Luo, Z. (2022). Nature Communications, 13, 3493. doi: 10.1038/s41467-022-31211-9
Off-the-Shelf Chimeric Antigen Receptor Immune Cells from Human Pluripotent Stem Cells (PDF)
Cao, H. and Sugimura, R. (2022). In: Hays, P. (eds) Cancer Immunotherapies. Cancer Treatment and Research, 183, Springer, Cham, 255-274. doi: 10.1007/978-3-030-96376-7_9
The Single-Cell Level Perspective of the Tumor Microenvironment and Its Remodeling by CAR-T Cells (PDF)
Gao, S. and Sugimura, R. (2022). In: Hays, P. (eds) Cancer Immunotherapies. Cancer Treatment and Research, 183, Springer, Cham, 275-285. doi: 10.1007/978-3-030-96376-7_10